DOUXO S3 PYO Combo Set – Shampoo (6.7 oz) Review
$18.95
The DOUXO® S3 PYO Combo Set includes a 6.7 oz shampoo and a 5.1 oz mousse designed to help manage bacterial and yeast-related skin issues in dogs. As the #1 vet-recommended topical brand, DOUXO S3 gently cleanses, soothes irritation, and helps reduce itching while supporting skin barrier health. Use the shampoo during the first week to thoroughly clean skin and coat, then follow with the mousse up to three times weekly for long-lasting results. Customers praise its effectiveness, pleasant scent, and ease of use. Not suitable for cats.
Product Details
- Brand: DOUXO® S3
- Includes: PYO Shampoo (6.7 oz) & PYO Mousse (5.1 oz)
- For dogs only (not for cats)
- Date First Available: February 7, 2024
- ASIN: B0CV5ZMFWS
- Rating: 4.7/5 stars (500 reviews)
Advantages
- Vet-recommended formula
- Helps relieve itching and irritation
- Supports healthy skin and coat
- Easy, step-by-step treatment routine
Our Recommendations
Ideal for dogs with recurring skin irritation or itching. Best results when shampoo and mousse are used together as directed.
Conclusion
The DOUXO® S3 PYO Combo Set is a reliable, vet-approved solution for managing dog skin problems, offering visible relief and quality care despite a higher price point.











Kaizoku –
Great doggie nose balm
This works very well for my dog who seems to have the world’s driest and crunchiest nose. Once applied, her nose regains it’s softness and feels a lot better. I can only imagine how it must feel for her. I highly recommend this product
alexis –
Works great on dry noses and skin
Night and day difference. I wish I took a picture of my dog’s rough and extremely dry nose. I applied the salve once every few days and my dog’s nose is smooth again. I tested a small amount on my hands to see if it would work on my dry hands and it worked beautifully. Once it’s warm the salve spreads like butter and goes straight into the pores.
Katie –
Works Wonders on our Lab
The stick balm has been great for our dog. He ended up with a large crack in his nose and the balm has been a game changer for him. I love that it is all natural, but doesn’t have an overwhelming smell. The size is great adn it is easy to apply, since it’s like a large chapstick (our dog is 105 pounds). It seems to prodive immediate relief and a softened touch to his nose once applied. We have repurchased this over time about three times now and will continue to purchase again. The only downside to the large stick is that it doesn’t turn like a normal chapstick, but turns up by the balm, so you will get balm on your hands and need to wash it off, however that is very minor.
Michael –
Works as described, non toxic
If used regularly it works well to help with your pups dry nose issue. Have purchased a few times now and will continue to use . Also like the fact its non toxic and the pup seems to like the taste. Licking tube helps to calm her while applying to nose and makes it easier.
Trina Christian –
Great for dry scratchy snouts!!!!
I purchased the trial size which is the size of a chapstick. I just wanted to test a small amount before getting the larger size. My dog Ross likes to dig holes in the yard with his snout ugh. His snout is always dry and rough. Ross is not a fan of ear cleanings, nail trims, or snout soothing. After my fiancé and I caught up with him and worked together we applied the snout soother. He licked it off right away, it’s tasty! So then we snuck it on with a little petting and treats and it made his nose look so hydrated!!! That was last night and today his snout still looks moisturized! It has a pleasant smell and is safe to lick! I will be purchasing a larger size! Perfect idea for our pup!
Karen C –
This really works!
My 13 yo Chihuahua has had hyperkeratosis (dry cracked nose), for several years. It causes them to lose their sense of smell, so I was concerned.I’ve tried Bag Balm, but he’d wipe it off by rubbing against his bed. It’s greasy and has a strange odor that might have annoyed him.It did nothing to help.I saw Snout Soother and since it was all natural I didn’t have high hopes.Was I ever surprised! I’ve only used it 6 days, 2 times a day and his nose has improved 98%It’s smoother and even wet again. He doesn’t mind it. No more rubbing to remove it. He stays still and seems to enjoy the application. It must be soothing on a dry cracked nose. .It’s not greasy and seems to soak right in.I’m going to continue until it’s 100%, and then use once a day to prevent the build up again. It’s not a curable condition, but it is treatable.I recommend this to anyone for their dogs dry cracked nose.Other reviewers say it works on paws too. My dogs paws are fine, but if it’s the same condition I’m sure it will work.
Darlene –
I stand behind this product 100% It’s AMAZING!!!
This product is amazing! It does EVERYTHING it says it does. Within two days my 16 year old dogs nose looked better than it had in years. The best thing about it was I never knew that this condition could affect his smell. His smell obviously returned (which I had no idea he couldn’t smell) and his appetite immediately picked up. He is partially blind and is deaf. Being able to have his smell back has totally changed him and improved his quality of life. I can’t say enough good things about this product. I wish I had taken before and after photos. Unfortunately I did not😔
Christine –
Stays put.
Perfect for super sensitive nose/mouth area! So much easier to use than the nasal oil emollients and much more effective because this ”Snout” stuff doesn’t drip out your nose, it stays put !! Another bonus is this stuff doesn’t have an offensive smell !! Both sides of my nose cracks, even smiling, sneezing or especially yawning will bring tears to my eyes, so the first time I used this stuff it was extremely comforting and I believe in time my cracks will be healed.Also I’m outside a lot and I don’t have to be constantly re-applying even tho’ the cold makes my nose run.
Francesca –
Ho scelto questa crema perché è totalmente naturale e visto che va messa sul naso, non volevo che potesse leccarsi roba chimica. Nel giro di 3 giorni il tartufo della mia Bulla Inglese è tornato idratato e morbidissimo!!! Ho provato a mettergliela anche su una zona della schiena, dove a causa di una ferita, le si era fatta ormai da mesi una cicatrice e non ricresceva più nessun pelo. Ho provato a mettergliela anche lì, tanto mi son detta è naturale e male che sarebbe andata, non sarebbe successo nulla, ma il pelo dopo 5 mesi che non cresceva più, le è rispuntato di nuovo!!!! Sono felicissima!!!!
Amazon カスタマー –
I used for about a week and I saw the significant improvements for our pups. I would definitely recommend.(They also like the taste and keep licking it.. so cute..)
Leonie Marx –
Der Stift ist zwar für seine Größe etwas teuer, erfüllt seinen Zweck aber wunderbar! Wie man an den vorher/nachher Fotos erkennen kann, sind die trockenen Stellen so gut wie verschwunden. Der Geruch ist meiner Meinung nach nicht neutral, aber auch nicht stark. Anfangs hat es meine Französische Bulldogge gestört, er hat sich aber daran gewöhnt. Alles in allem ein gutes Produkt, welches ich empfehlen kann.
Hayley Rose –
Our go to balm for when our dogs noses are dry… definitely the best one we have come across
Laky –
Hace su función. Tal como se describe